Building international-quality APIs through patented technologies.

Building international-quality APIs through patented technologies.

Deeply committed to the research and production of active pharmaceutical ingredients, with quality certified by international authorities.
20 Years of Expertise – The Trusted Choice for Chemical APIs

20 Years of Expertise – The Trusted Choice for Chemical APIs

Professional R&D and production of chemical APIs, with quality aligned to FDA and EDQM standards.
Shiji APIs Connect Global Health

Shiji APIs Connect Global Health

Compliance as the Foundation, Innovation as the Driver—Bringing High-Quality Active Pharmaceutical Ingredients to the World
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Company Profile

About Shiji Pharmaceutical

Professional pharmaceuticals, unwavering dedication, serving global customers.

Wuhan Shiji Pharmaceutical is a high-tech pharmaceutical company headquartered in Wuhan with global reach. It specializes in the R&D, manufacturing, and import‑export of chemical APIs, leveraging internationally recognized certifications, proprietary patented technologies, and a robust GMP‑compliant production system. The company provides high‑quality APIs that meet global standards, along with expert services, to pharmaceutical enterprises worldwide, striving to become an internationally acclaimed supplier of premium chemical APIs.
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027-83097557 Service Hotline

2005 year

The company was founded in 2005.

5000 Ten thousand

The registered capital provides a solid guarantee for R&D investment.

20 year

Focused on the R&D and production of chemical APIs.

200 person

Company’s R&D and Production Team

34 item

Backed by 34 proprietary patents

Product Center

PRODUCT CENTER

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Active pharmaceutical ingredient

Active pharmaceutical ingredient

Clozapine Galantamine Hydrobromide View All Products

Intermediate

Intermediate

Clozapine cyclization compound Benserazide EP Impurity A View All Products

Veterinary medicine

Veterinary medicine

Atemizole hydrochloride Oxazepam hydrochloride View All Products

Cosmetic ingredients

Cosmetic ingredients

Thioxazone Vitamin C ethyl ether View All Products

Featured Product

FEATURED PRODUCTS

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Clozapine

CAS号： 5786-21-0

化学名： 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine

Galantamine Hydrobromide

CAS号： 1953/4/4

化学名： (4aS,6R,8aS)-5,6,9,10,11,12-Hexahydro-3-methoxy-11-methyl-4aH-benzo[furano[3a,3,2-ef][2]benzazepine-6-ol hydrobromide

Benserazide hydrochloride

CAS号： 14919-77-8

化学名： DL-Serine-2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride

Nicorandil

CAS号： 65141-46-0

化学名： N-(2-Nitroxyethyl)pyridine-3-carboxamide

Warfarin sodium

CAS号： 129-06-6

化学名： Sodium salt of 3-(3-oxo-1-phenylbutyl)-4-hydroxy-2H-1-benzo-pyran-2-one with isopropanol

Potassium nitrate

CAS号： 7757-79-1

化学名： Potassium nitrate

Butylphenol

CAS号： 6066-49-5

化学名： 3-Butylphthalide

Xiteng Xiping

CAS号： 98374-54-0

化学名： 11-[2-[Bis(2-hydroxyethyl)amino]acetyl]-3-chloro-5H-benzo[b][1,4]benzodiazepine-6-one

Clozapine cyclization compound

CAS号： 50892-62-1

化学名： 8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one

Benserazide EP Impurity A

CAS号： 55819-71-1

化学名： DL-Serinylhydrazine hydrochloride

Nicorandil EP Impurity B

CAS号： 6265-73-2

化学名： N-(2-Hydroxyethyl)-3-pyridinecarboxamide

Warfarin

CAS号： 81-81-2

化学名： 3-(1-Propionylbenzyl)-4-hydroxycoumarin

Quinuclidine cyclization compound

CAS号： 3159/7/7

化学名： Dibenzo[b,f][1,4]thiazepin-11-one-10H

Amoxapine intermediate

CAS号： 3158-91-6

化学名： 2-Chlorodibenzo[b,f][1,4]oxazepin-11(10H)-one

Alprazolam intermediate

CAS号： 4547/2/8

化学名： 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione

Atemizole hydrochloride

CAS号： 104075-48-1

化学名： 4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazolium hydrochloride

Oxazepam hydrochloride

CAS号： 31352-82-6

化学名： 4-(2-Fluorophenyl)-6,8-dihydro-1,3,8-trimethylpyrazolo[3,4-e][1,4]diazepin-7(1H)-one

Tiloxapine hydrochloride

CAS号： 14176-50-2

化学名： 2-(Ethylamino)-2-(2-thienyl)cyclohexanone hydrochloride

Thioxazone

CAS号： 4991-65-5

化学名： 6-Hydroxy-1,3-benzothiazol-2-one

Vitamin C ethyl ether

CAS号： 86404-04-8

化学名： 3-O-Ethyl-L-ascorbic acid

Core Advantages

CORE ADVANTAGE

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International Compliance Advantages

Backed by dual certifications, it enjoys seamless access to the global market.

Certified by the U.S. FDA and the EU’s EDQM, we have established a GMP‑compliant quality management system; our products meet both domestic and international pharmacopoeial standards, helping customers seamlessly access global markets.

Technological R&D Advantages

34 patents, innovation driving quality

With 34 proprietary patents, our core R&D team has been deeply engaged in the API field for many years, boasting extensive expertise in synthetic process optimization and impurity control, and continuously driving product performance enhancements.

Steady Strength and Advantages

Dual assurance of capital and production capacity, ensuring worry-free delivery.

With RMB 50 million in paid-in capital underpinning its operational foundation, and a garden‑style facility spanning over 60,000 square meters equipped with a full suite of precision manufacturing equipment, the company boasts stable, large‑scale production capabilities, ensuring rapid order fulfillment and on‑time delivery.

News and Information

NEWS INFORMATION

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Definition and classification of the chemical API industry, along with its industrial value chain and market competitive landscape.

12-26

2022

Definition and classification of the chemical API industry, along with its industrial value chain and market competitive landscape.

Chemical active pharmaceutical ingredients (APIs) refer to the raw materials used in the manufacture of various dosage forms; they constitute the active components of these formulations. APIs are prepared through chemical synthesis, plant extraction, or biotechnological processes and exist in forms such as powders, crystals, or extracts—substances that cannot be administered directly to patients.

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Definition and Classification of the Chemical API Industry

12-23

2022

Definition and Classification of the Chemical API Industry

Chemical API manufacturing refers to the production of active pharmaceutical ingredients required for the further processing of drug formulations. It is classified under the pharmaceutical manufacturing industry (C27), with a four-digit statistical code of 2710.

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What is the difference between chemical APIs and chemical products?

12-16

2022

What is the difference between chemical APIs and chemical products?

Specifically, after the active pharmaceutical ingredient (API) has been processed into a drug formulation, the term “API” is used primarily in contrast to the finished dosage form. APIs are mainly obtained through chemical synthesis and serve as the raw materials for manufacturing finished pharmaceutical products; for example, cefoperazone sulfate for injection is a drug, and cefoperazone sulfate itself is the API.

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Active pharmaceutical ingredients are classified into two major categories based on their source: chemically synthesized drugs and naturally derived chemical drugs.

12-06

2022

Active pharmaceutical ingredients are classified into two major categories based on their source: chemically synthesized drugs and naturally derived chemical drugs.

Natural chemical drugs, according to their sources, can also be classified into two major categories: biochemical drugs and phytochemical drugs. Antibiotics are generally produced through microbial fermentation and fall under the purview of biochemistry.

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What is medical adhesive-coated paper like?

11-16

2022

What is medical adhesive-coated paper like?

Medical adhesive-coated paper is primarily used for medical packaging, helping to safeguard the quality of medical products, prevent oxidation and degradation, and enhance product stability. Let’s examine the quality standards for this type of paper. Strict requirements are imposed on its quality: the surface must be clean and smooth, with even and symmetrical coating; printing of text and graphics must be accurate, clear, and durable. The paper should also be free from dense, continuous pinholes. Furthermore, there should be no color variation between different batches of medical aluminum foil; any noticeable color discrepancy renders the product non‑conforming. Medical packaging meets the expectations of medical product manufacturers and demonstrates compliance with established quality standards by integrating a quality management system and Good Manufacturing Practices throughout the production process. Traceability in medical adhesive‑coated paper means that suppliers can clearly identify the origin of their products and the raw materials used in their manufacture. Ensuring traceability is essential for protecting the health of patients and the public at large. Should any issues arise, the raw materials and manufacturing processes employed by CNC cutting machines can be traced back to the customer. 1. If defects are detected, manufacturers can readily investigate the root causes and employ quality control systems to pinpoint initial errors and address them. 2. Moreover, traceability ensures that the sources and quality of raw materials are reliable, thereby guaranteeing product integrity and safe production.

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Advantages of Medical Composite Films

10-27

2022

Advantages of Medical Composite Films

Medical composite films, owing to aluminum’s softness, excellent ductility, and silvery luster, can be laminated onto offset paper using sodium silicate or similar binders to produce aluminum foil sheets suitable for printing. Consequently, they are widely used in packaging for food, beverages, tobacco, pharmaceuticals, and more. Next, let’s explore the advantages of medical composite films. Traditionally, medical composite films undergo high‑temperature sterilization during production; however, their thermal insulation performance is relatively poor, and the sterilization temperature must not be excessively high. Otherwise, the film may suffer heat damage, compromising its sterilization efficacy. Thus, the thermal insulation properties of conventional medical composite films remain in need of improvement. Furthermore, during transportation, sales, and use, bacteria can adhere to both the inner and outer surfaces of the packaging film, leading to contamination. Conventional medical composite films also exhibit poor resistance to aging, making them prone to degradation during storage, transport, and application. Once aged, such films can no longer provide reliable protection for the contained pharmaceuticals. In addition, aged films tend to attract dirt and contaminants, which may adhere to tablets, causing drug deterioration and adversely affecting medication safety. In view of these shortcomings of existing technologies, the objective of this utility model is to provide a medical composite film that delivers robust, long‑lasting antibacterial efficacy while simultaneously offering superior thermal insulation and self‑cleaning capabilities. To achieve this goal, a structure is proposed, starting from the left…

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Preparation Method of Medical Composite Film

10-17

2022

Preparation Method of Medical Composite Film

A medical composite membrane material containing polyurethane and acetate‑starch, wherein the use of acetate‑starch in this invention enhances the breathability of the medical composite membrane. Furthermore, acetate‑starch particles absorb internal water molecules and, under external pressure, rapidly diffuse into the composite membrane. The incorporation of these acetate‑starch particles enables an alkaline aqueous solution to adsorb onto their surfaces, disrupting the dense internal structure of the polyurethane matrix, thereby creating additional pathways for water molecules and improving both the air permeability and moisture vapor transmission of the medical composite membrane. Next, let us examine the preparation method of this medical composite membrane. This invention pertains to the field of medical materials and is designed to prevent subcutaneous tissue edema; when skin injuries occur, timely dressing application is essential to protect the wound and alleviate pain. Currently, commonly used dressings include cotton cloth and gauze, yet they lack moisturizing properties, readily form scabs, and their permeability can lead to exogenous infections. Although soft in texture and possessing strong absorbency with some protective effects on wounds, such materials often fail to meet clinical requirements and may elicit rejection reactions in humans. Biologically derived materials like pigskin and sheepskin, widely employed in clinical practice, suffer from deficiencies in strength, elasticity, moisture permeability, and moisture‑wicking capabilities, while limitations in storage and transportation further hinder their large‑scale application. Medical composite membranes have already found applications in the medical field.

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Why is a medical composite film necessary?

10-08

2022

Why is a medical composite film necessary?

The Medical Composite Film Application Report segments the industry by type, application, and research region, examining the growth strategies adopted by key companies. The market size section presents revenue data for medical composite films, covering both historical performance and future projections. The report also includes valuable insights drawn from diverse industry sources, analyzing the competitive landscape based on company profiles and efforts to enhance product value and output. Next, let’s explore why medical composite films are essential. Medical composite films are primarily used to identify raw material substrates and select appropriate compositional layers to create multi‑layer composite films, tailored to specific application requirements; additional components are prevented from migrating back to the film surface. Substances that pass through the membrane are referred to as permeates, while residual substances are called concentrates. In the healthcare sector, various types of films are employed depending on the required barrier properties. This report highlights the preparation, characteristics, and performance of medical composite films in medical, environmental, and energy applications. The main materials include polymeric, inorganic, and composite aluminum‑foil films. It also discusses promising aluminum‑foil film technologies and potential commercial pathways for advancing and enhancing drug delivery, wound healing, tissue engineering, water and wastewater treatment and purification, gas separation and purification, air purification, and fuel cell technologies. Key features of medical composite films: 分

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Applications and Packaging Advantages of Medical Composite Films

09-27

2022

Applications and Packaging Advantages of Medical Composite Films

Economic losses caused by corrosion are estimated to account for about 3% to 4% of the total economic output, making medical composite films particularly important. Let’s now explore the applications and packaging advantages of these films. There are many ways to prevent or mitigate corrosion—for example, employing electrochemical protection or using thin films as barriers against corrosive agents such as moisture and oxygen. One common and cost-effective anti-corrosion approach is to apply a protective coating system onto metal surfaces, creating a barrier between the metal and the corrosive environment. Additionally, incorporating materials like zinc can provide electrochemical protection to the coating. Numerous anti-corrosion coatings exhibit excellent performance in harsh environments. Given the critical importance of drug safety, stringent requirements are imposed on the properties of external packaging materials—especially their ability to effectively block external water vapor, thereby preventing medication from absorbing moisture and degrading. With the exception of traditional Chinese medicine decoction pieces and low‑grade perforated packaging, most medical composite films are based on multilayer structures containing pure aluminum foil. These films serve as outer packaging bags for powdered medications or as backing layers in blister packs. Beyond enhancing the aesthetic appeal and tactile quality of pharmaceutical packaging, they offer another key advantage: their superior barrier properties against water vapor, typically quantified by water vapor transmission rate. The lower this value, the better the moisture resistance, helping to prevent drugs from becoming damp and deteriorating. As laser technology continues to expand into an ever‑wider range of applications…

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Profit Ranking of China’s Chemical API Industry in the First Half of 2019

06-12

2019

Profit Ranking of China’s Chemical API Industry in the First Half of 2019

According to the ranking, a total of 68 companies in China’s chemical API industry made the list in the first half of 2018. Among the top ten enterprises in terms of combined net profit for NEEQ‑listed companies in this sector during the same period were: Hequan Pharmaceutical, Yuxing Bio, Yaoshi Technology, Chetou Pharmaceutical, Fushilai, Huanglong Pharmaceutical, and Xianfeng Technology, among others.

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